Saturday, February 24, 2018

Cholesterol / Blood Glucose

LDL-C normal-100 mg/dL, borderline-130, high-160.  
LDL-P Labcorp 
LP(a) Lipoprotein(a) 
- LDL size patterns, large low density LDL particles are described as pattern A, and small high density LDL particles are pattern B. 
- A correspondence between higher triglyceride levels and higher levels of smaller, denser LDL particles and alternately lower triglyceride levels and higher levels of the larger, less dense ("buoyant") LDL.  
- A stronger correlation between human clinically obvious cardiovascular events and quantitatively measured particle concentrations.  
HDL 
Total Cholesterols < 200 
Triglyceride 

1. Statin lipid-lowering medication
Consumer Reports Statins Update: Pravastatin Pravachol, Simvastatin Zocor 

Reduction of heart attacks: Atorvastatin (Lipitor), Lovastatin (Altoprev), Pravastatin (Pravachol), Simvastatin (Zocor), Rosuvastatin (Crestor) 

Reduction of deaths: Atorvastatin (Lipitor), Pravastatin (Pravachol), Simvastatin (Zocor) 

Muscle damage: hydrophilic statins (fluvastatin, rosuvastatin Crestor 5/10/20/40/80mg, pravastatin), are less toxic than lipophilic statins (atorvastatin Lipitor, lovastatin, and simvastatin Zocor) 

Ezetimibe (Zetia) inhibits the absorption of dietary cholesterol from the intestine 
** combination medication: Ezetimibe/rosuvastatin 10mg+5/10/20/40mg 

Crestor 冠脂妥 rosuvastatin 魯士定 10mg 39%-46% 

2. PCSK9 
Alirocumab Praluent
Evolocumab Repatha

Tradjenta 糖漸平 Linagliptin 5mg DPP-4 

You-jet 憂解 Zoloft Sertraline 50mg 

Loata 羅達 Cilostazol 50mg 

Xanax 贊安諾 Alprazolam 0.25mg 

Diabetes, type 2 Glycated hemoglobin HbA1c, A1c < 5.7%; > 6.4% Blood sugar level 
Testing for DiabetesTesting for Diabetes and Prediabetes: A1C goal < 7%, fasting - 99 100-125 126-, glucose tolerance 75g 2 hours -139 140-199 200-, diabetes 200, Prevention of type 2 diabetes 
Monitoring Your Blood Sugar, target range: before meals 80-130, 1-2 hours later < 180 
Prediabetes A1c 5.7-6.4, impared Glucose tolerance test 140-199 75g glucose, Impaired fasting glucose 100/110-125 

1, Biguanide (Metformin) decrease glucose production in the liver, increase insulin sensitivity, reduce appetite 
2, SGLT2 Empagliflozin (Jardiance) inhibit reabsorption of glucose in the kidney
3, DPP-4 Linagliptin (Tradjenta) increase production of insulin, decrease production of glucagon, increase GLP-1 
4, GLP-1 reduce blood sugar and energy intake by activating the GLP-1 receptor 


Senseonics Eversense E3 90 days, XL 180 days, 365 days in 2025 
Over The Counter OTC cgmDexcom Stelo AI, Abbott Lingo 

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